Membrance Proteofetch Array is to express membrane proteins in a natural state directly in cells, keeping their structural integrity and natural post-translational modification, and on this basis, to form a cell array, which is used to identify the targeting specificity of antibodies, drugs or other ligands that bind to membrane proteins, and to provide a comprehensive cross-reaction assessment for the new regulatory requirements of IND declaration of CAR-T, antibodies and other drugs. At the same time, this technique can also be used in many fields, such as new target discovery, virus mechanism analysis, ligand-receptor de-orphaning .
